PHACTR3-AS1

Across TCGA pan-cancer cohorts, PHACTR3-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of PHACTR3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PHACTR3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PHACTR3-AS1 is over-expressed in tumor, although a few such as STAD and LUSC show the opposite, repressed pattern.

KIRC, STAD, and LUSC are the cancer types where PHACTR3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PHACTR3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.092	.001	6	view →
STAD	Male	All	−0.020	.016	1	view →
LUSC	All	II,III,IV	−0.013	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

PHACTR3-AS1–KIRC

Open the KIRC breakdown →