PGBD5

Across TCGA cell cohorts, PGBD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,381 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PGBD5-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with PGBD5 in more than 14 cancer types. Because this analysis shows association rather than direction, both PGBD5-to-partner and partner-to-PGBD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by PGBD5-low versus PGBD5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD5→partner) and Y-score (partner→PGBD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.167	+1.081	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.173	+1.081	<.001	<.001	3	15
OESOPHAGUS	Regulation of myoblast fusion →	+0.141	+1.081	<.001	<.001	3	13
OESOPHAGUS	Electron transport chain →	+0.124	+1.286	<.001	<.001	3	12
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.138	+1.077	<.001	<.001	2	13
UPPER_AERODIGESTIVE_TRACT	Regulation of ubiquitin-dependent protein catabolic process →	+0.059	+1.780	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,381 associations by consensus.

Negative regulation of myoblast fusion by PGBD5 expression — OESOPHAGUS

Explore this box plot interactively →