PFKM

Across TCGA patient cohorts, PFKM RNA expression is significantly associated with the protein abundance of many other proteins, with 13,674 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PFKM-associated proteins across cancer lineages are PFKM_S377, P4HB, and SDF2L1. Each is linked with PFKM in more than 6 cancer types. Because this analysis shows association rather than direction, both PFKM-to-partner and partner-to-PFKM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PFKM versus PFKM_S377 in BRCA, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PFKM→partner) and Y-score (partner→PFKM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PFKM_S377 →	+1.536	+1.615	<.001	<.001	3	7
GBM	P4HB →	-0.374	-0.334	<.001	<.001	3	5
LSCC	SDF2L1 →	-0.435	-0.853	<.001	<.001	3	5
OV	TNFAIP8 →	-0.624	-0.585	.003	.001	3	4
LSCC	UBE2J1 →	-0.450	-0.584	<.001	<.001	3	4
LUAD	PDIA4 →	-0.342	-0.318	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,674 associations by consensus.

PFKM vs PFKM_S377 — BRCA

Explore this scatter interactively →