PFKL

Across TCGA patient cohorts, PFKL RNA expression is significantly associated with the protein abundance of many other proteins, with 8,287 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PFKL-associated proteins across cancer lineages are SCP2, ALDH1L2, and MYO5A. Each is linked with PFKL in more than 3 cancer types. Because this analysis shows association rather than direction, both PFKL-to-partner and partner-to-PFKL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PFKL versus SCP2 in UCEC, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PFKL→partner) and Y-score (partner→PFKL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SCP2 →	+0.299	+0.880	.003	.002	3	4
CCRCC	ALDH1L2 →	-0.613	-0.408	<.001	<.001	3	4
UCEC	MYO5A →	-0.472	-0.963	<.001	.003	3	4
LUAD	SPCS3 →	-0.393	-0.528	.003	<.001	2	4
LSCC	MZB1 →	-0.790	-0.415	<.001	<.001	3	3
LSCC	NANS →	-0.341	-0.471	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,287 associations by consensus.

PFKL vs SCP2 — UCEC

Explore this scatter interactively →