PFKL

Across TCGA patient cohorts, PFKL protein abundance is significantly associated with the protein abundance of many other proteins, with 17,334 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PFKL-associated proteins across cancer lineages are FCSK, INF2, and PDK1. Each is linked with PFKL in more than 7 cancer types. Because this analysis shows association rather than direction, both PFKL-to-partner and partner-to-PFKL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PFKL versus FCSK in CCRCC, with a Pearson correlation of 0.64.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PFKL→partner) and Y-score (partner→PFKL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FCSK →	+0.397	+0.349	<.001	<.001	3	8
BRCA	INF2 →	+0.430	+0.251	<.001	<.001	3	6
UCEC	PDK1 →	+0.519	+0.241	<.001	<.001	3	6
PDAC	PDXK →	+0.323	+0.215	<.001	<.001	3	6
CCRCC	AGL →	+0.399	+0.367	<.001	<.001	3	6
CCRCC	GYS1 →	+0.447	+0.288	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,334 associations by consensus.

PFKL vs FCSK — CCRCC

Explore this scatter interactively →