PEX5L

Across TCGA patient cohorts, PEX5L protein abundance is significantly associated with the RNA expression of many other genes, with 4,632 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PEX5L-associated genes across cancer lineages are HS6ST3, CDC37P1, and ITM2A. Each is linked with PEX5L in more than 1 cancer types. Because this analysis shows association rather than direction, both PEX5L-to-partner and partner-to-PEX5L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEX5L versus HS6ST3 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX5L→partner) and Y-score (partner→PEX5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HS6ST3 →	+1.419	+0.759	<.001	<.001	3	2
BRCA	CDC37P1 →	-0.352	-1.042	.004	.002	3	2
OV	ITM2A →	+2.305	+2.079	.007	<.001	3	2
BRCA	LANCL1 →	+0.735	+0.704	.008	.008	3	2
BRCA	MAPK8IP1 →	+1.401	+1.287	.002	.003	3	2
BRCA	SYT4 →	+2.241	+0.916	.008	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,632 associations by consensus.

PEX5L vs HS6ST3 — GBM

Explore this scatter interactively →