PEX5

Across TCGA patient cohorts, PEX5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,257 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PEX5-associated proteins across cancer lineages are CMAS, TPI1, and MLF2. Each is linked with PEX5 in more than 5 cancer types. Because this analysis shows association rather than direction, both PEX5-to-partner and partner-to-PEX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEX5 versus CMAS in OV, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX5→partner) and Y-score (partner→PEX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CMAS →	+0.448	+0.578	<.001	<.001	3	6
OV	TPI1 →	+0.679	+0.867	<.001	<.001	3	6
LSCC	MLF2 →	+0.513	+0.637	<.001	<.001	3	6
LSCC	USP5 →	+0.313	+0.691	<.001	<.001	3	6
HNSC	WBP11 →	+0.268	+0.637	.001	<.001	3	5
LSCC	FKBP4 →	+0.577	+0.682	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,257 associations by consensus.

PEX5 vs CMAS — OV

Explore this scatter interactively →