PEX5

Across TCGA patient cohorts, PEX5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,910 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PEX5-associated genes across cancer lineages are RIMKLB, PLEKHA5, and XAF1. Each is linked with PEX5 in more than 3 cancer types. Because this analysis shows association rather than direction, both PEX5-to-partner and partner-to-PEX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEX5 versus RIMKLB in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX5→partner) and Y-score (partner→PEX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIMKLB →	+0.833	+0.348	<.001	<.001	3	4
LUAD	PLEKHA5 →	+0.665	+0.187	<.001	<.001	3	4
HNSC	XAF1 →	-0.916	-0.274	<.001	<.001	2	4
LSCC	RPL13P5 →	+0.420	+0.190	<.001	<.001	3	3
BRCA	AKNA →	-0.668	-0.214	<.001	.009	3	3
HNSC	ARHGAP25 →	-0.665	-0.235	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,910 associations by consensus.

PEX5 vs RIMKLB — LSCC

Explore this scatter interactively →