PEX5

Across TCGA cell cohorts, PEX5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,388 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PEX5-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, RNA catabolic process, and mRNA catabolic process. Each is linked with PEX5 in more than 12 cancer types. Because this analysis shows association rather than direction, both PEX5-to-partner and partner-to-PEX5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by PEX5-low versus PEX5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX5→partner) and Y-score (partner→PEX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of nucleotide-excision repair →	+0.172	+0.935	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	RNA catabolic process →	+0.067	+0.834	<.001	.001	2	13
BONE	mRNA catabolic process →	+0.057	+0.609	.002	.008	3	12
PANCREAS	Protein-DNA complex disassembly →	+0.123	+0.897	<.001	.004	3	12
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.079	+0.850	.003	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA repair →	+0.069	+0.785	.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,388 associations by consensus.

Regulation of nucleotide-excision repair by PEX5 expression — STOMACH

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