PEX13

Across TCGA patient cohorts, PEX13 mutation is significantly associated with the RNA expression of many other genes, with 2,769 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PEX13-associated genes across cancer lineages are SNORA37, USP12PY, and RPSAP59. Each is linked with PEX13 in more than 1 cancer types. Because this analysis shows association rather than direction, both PEX13-to-partner and partner-to-PEX13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA37 grouped by PEX13-low versus PEX13-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX13→partner) and Y-score (partner→PEX13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNORA37 →	+1.780	+3.840	<.001	.005	3	2
BLCA	USP12PY →	+0.093	+5.685	<.001	.003	3	2
LIHC	RPSAP59 →	+0.024	+4.878	.008	.005	3	2
COAD	TRAJ58 →	+0.978	+3.686	<.001	.005	3	2
COAD	LINC02647 →	+0.285	+5.142	<.001	.002	3	2
COAD	PLCL2-AS1 →	+0.675	+3.899	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,769 associations by consensus.

SNORA37 by PEX13 expression — COAD

Explore this box plot interactively →