PEX13

Across TCGA pan-cancer cohorts, PEX13 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated PEX13 data layer compared with 2 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PEX13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PEX13 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PRAD show a favorable association.

ACC, KIRC, and PAAD are the cancer types where PEX13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.408	0.748	<.001	80	view →
KIRC	DFS	Tertile	All	0.792	0.454	<.001	64	view →
PAAD	OS	Median	All	0.274	0.535	<.001	51	view →
LGG	OS	Median	All	0.745	0.883	<.001	51	view →
HNSC	OS	Quartile	III,IV	0.525	0.701	.020	36	view →
UVM	DFS	Quartile	III,IV	0.182	0.813	.003	31	view →
LIHC	OS	Median	All	0.727	0.824	.005	31	view →
KICH	DFS	Median	III,IV	0.318	0.901	.004	23	view →
KIRP	OS	Median	III,IV	0.284	0.616	.011	20	view →
PRAD	DFS	Quartile	All	0.948	0.834	.002	18	view →
CESC	DFS	Median	III,IV	0.462	0.748	.020	12	view →
COAD	OS	Tertile	All	0.954	0.817	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

PEX13–ACC (DFS)

Open the ACC breakdown →