PES1

Across TCGA patient cohorts, PES1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,269 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PES1-associated proteins across cancer lineages are TRMT2A, SMC4, and CHEK2. Each is linked with PES1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PES1-to-partner and partner-to-PES1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PES1 versus TRMT2A in BRCA, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PES1→partner) and Y-score (partner→PES1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRMT2A →	+0.410	+0.543	<.001	<.001	3	7
HNSC	SMC4 →	+0.483	+1.207	<.001	.001	3	6
OV	CHEK2 →	+0.552	+0.470	.002	.005	3	6
BRCA	MDN1 →	+0.318	+0.517	<.001	<.001	3	6
OV	EIF4A1 →	+0.365	+0.657	<.001	<.001	3	6
LSCC	RANBP1 →	+0.390	+0.537	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,269 associations by consensus.

PES1 vs TRMT2A — BRCA

Explore this scatter interactively →