PER3

Across TCGA patient cohorts, PER3 mutation is significantly associated with the RNA expression of many other genes, with 5,963 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PER3-associated genes across cancer lineages are RCC1, LINC00909, and MTFP1. Each is linked with PER3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PER3-to-partner and partner-to-PER3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RCC1 grouped by PER3-low versus PER3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PER3→partner) and Y-score (partner→PER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RCC1 →	+0.470	+2.949	<.001	<.001	3	4
COAD	LINC00909 →	+0.369	+2.595	.003	.006	3	3
UCEC	MTFP1 →	+0.480	+2.534	<.001	<.001	3	3
UCEC	CENPU →	+0.834	+1.949	<.001	<.001	3	3
UCEC	ATP5MC3 →	+0.344	+1.776	.004	<.001	3	3
UCEC	MRPL39 →	+0.487	+1.733	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,963 associations by consensus.

RCC1 by PER3 expression — UCEC

Explore this box plot interactively →