PER3

Across TCGA cell cohorts, PER3 mutation is significantly associated with the RNA expression of many other genes, with 157 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PER3-associated genes across cancer lineages are VN1R2, SLC38A8, and KRTAP12-2. Each is linked with PER3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PER3-to-partner and partner-to-PER3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R2 grouped by PER3-low versus PER3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PER3→partner) and Y-score (partner→PER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	VN1R2 →	+0.008	+3.269	.004	.007	3	2
LARGE_INTESTINE	SLC38A8 →	+0.537	+2.626	<.001	.006	3	2
LARGE_INTESTINE	KRTAP12-2 →	+0.032	+2.538	<.001	.005	3	2
CNS	ASB10 →	+0.049	+4.566	<.001	.001	3	2
CNS	OR5A1 →	+0.730	+4.566	<.001	.001	3	2
CNS	ARGFX →	+0.081	+3.832	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 157 associations by consensus.

VN1R2 by PER3 expression — BLOOD_Leukemia

Explore this box plot interactively →