PEF1

Across TCGA patient cohorts, PEF1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,801 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PEF1-associated genes across cancer lineages are RSRP1, LDLRAP1, and MASP2. Each is linked with PEF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PEF1-to-partner and partner-to-PEF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEF1 versus RSRP1 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEF1→partner) and Y-score (partner→PEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RSRP1 →	+0.550	+0.312	.007	.002	3	4
LSCC	LDLRAP1 →	+0.546	+0.227	<.001	<.001	3	4
BRCA	MASP2 →	+0.500	+0.287	<.001	<.001	3	4
LUAD	MTFR1L →	+0.429	+0.237	<.001	<.001	3	4
LUAD	NIPAL3 →	+0.749	+0.282	<.001	<.001	3	3
BRCA	BSDC1 →	+0.455	+0.307	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,801 associations by consensus.

PEF1 vs RSRP1 — BRCA

Explore this scatter interactively →