PEBP4

Across TCGA patient cohorts, PEBP4 mutation is significantly associated with the RNA expression of many other genes, with 92 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PEBP4-associated genes across cancer lineages are LINC02222, SAPCD2P2, and OR2T33. Each is linked with PEBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PEBP4-to-partner and partner-to-PEBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02222 grouped by PEBP4-low versus PEBP4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEBP4→partner) and Y-score (partner→PEBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02222 →	+0.027	+5.199	.001	.003	3	2
UCEC	SAPCD2P2 →	+0.064	+3.488	.001	.008	3	2
COAD	OR2T33 →	+0.081	+4.246	.004	<.001	3	1
UCEC	MIR6780B →	+0.560	+3.889	<.001	.004	3	1
LUAD	MIR6879 →	+0.686	+7.930	<.001	.008	3	1
SKCM	LINC00208 →	+0.016	+5.624	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

LINC02222 by PEBP4 expression — SKCM

Explore this box plot interactively →