PDZRN4

Across TCGA patient cohorts, PDZRN4 protein abundance is significantly associated with the RNA expression of many other genes, with 298 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDZRN4-associated genes across cancer lineages are DICER1, PHF7, and STUB1. Each is linked with PDZRN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDZRN4-to-partner and partner-to-PDZRN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZRN4 versus DICER1 in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZRN4→partner) and Y-score (partner→PDZRN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DICER1 →	+0.751	+0.741	.001	.001	3	1
GBM	PHF7 →	-0.413	-0.620	.004	.005	3	1
GBM	STUB1 →	-0.676	-0.586	.008	.001	3	1
GBM	MAZ →	-0.673	-0.568	.004	.006	3	1
GBM	SLC30A4 →	+0.409	+0.521	.005	.003	3	1
GBM	BLOC1S6 →	+0.528	+0.714	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 298 associations by consensus.

PDZRN4 vs DICER1 — GBM

Explore this scatter interactively →