Across TCGA patient cohorts, PDZK1P1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDZK1P1-associated genes across cancer lineages are MIR668, RNU6-1211P, and UGT2B10. Each is linked with PDZK1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDZK1P1-to-partner and partner-to-PDZK1P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZK1P1→partner) and Y-score (partner→PDZK1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR668 →	+0.308	+7.816	<.001	.008	3	1
SKCM	RNU6-1211P →	+0.283	+7.816	<.001	.008	3	1
UCEC	UGT2B10 →	+0.346	+3.041	<.001	.008	3	1
UCEC	LINC02563 →	+0.224	+4.005	<.001	.002	3	1
UCEC	RPL31P9 →	+0.284	+4.132	<.001	.009	3	1
UCEC	CORO1CP1 →	+0.101	+4.279	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

PDZK1P1 survival (RNA) · tumor vs normal (RNA) · all PDZK1P1 data types