Q-omics provides the consensus-scored CORO1CP1 profile across patient tissues and cancer cell-line models. CORO1CP1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, CORO1CP1 is differentially expressed in 3, with the highest sampling consensus in THCA. Additionally, CORO1CP1 RNA expression shows 12,156 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight READ, THCA, and LAML as cancer lineages where CORO1CP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CORO1CP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CORO1CP1 survival associations across molecular data types. CORO1CP1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CORO1CP1 RNA expression–survival associations across cancer types. High CORO1CP1 expression shows unfavorable associations in READ, DLBC, CHOL, MESO and KIRP, but favorable associations in LAML. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify READ as the clearest survival context for CORO1CP1 RNA expression.
This table summarizes CORO1CP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for CORO1CP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CORO1CP1 shows lower tumor expression in THCA and higher tumor expression in KIRC and LIHC. The THCA box plot shows higher CORO1CP1 RNA expression in normal versus tumor tissue (log2 FC = −0.025, t-test p = .003).
This table shows molecular features associated with CORO1CP1 in patient tissues and cancer cell lines. In patient samples, CORO1CP1 shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
