Across TCGA cell cohorts, PDZD7 mutation is significantly associated with the RNA expression of many other genes, with 196 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PDZD7-associated genes across cancer lineages are ADAM29, KRT82, and C12orf54. Each is linked with PDZD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDZD7-to-partner and partner-to-PDZD7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD7→partner) and Y-score (partner→PDZD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ADAM29 →	+0.029	+3.938	<.001	.005	3	2
OVARY	KRT82 →	+0.009	+3.700	<.001	.005	3	1
OVARY	C12orf54 →	+0.580	+4.643	<.001	<.001	3	1
OVARY	P2RY13 →	+0.011	+3.791	.005	.007	3	1
BLOOD_Leukemia	NXPE4 →	+0.027	+4.276	<.001	.007	3	1
BLOOD_Leukemia	ASZ1 →	+0.132	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 196 associations by consensus.

Exploration

PDZD7 survival (RNA) · tumor vs normal (RNA) · all PDZD7 data types