PDZD11

Across TCGA patient cohorts, PDZD11 protein abundance is significantly associated with the RNA expression of many other genes, with 12,649 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDZD11-associated genes across cancer lineages are PLEKHA5, CSF2RB, and IL21R. Each is linked with PDZD11 in more than 9 cancer types. Because this analysis shows association rather than direction, both PDZD11-to-partner and partner-to-PDZD11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZD11 versus PLEKHA5 in GBM, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD11→partner) and Y-score (partner→PDZD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEKHA5 →	+1.325	+0.561	<.001	<.001	3	10
COAD	CSF2RB →	-0.934	-0.206	<.001	<.001	3	6
OV	IL21R →	-0.881	-0.369	<.001	.001	3	6
LSCC	MANSC1 →	+0.856	+0.283	<.001	<.001	3	6
GBM	ADAM19 →	-0.910	-0.474	.003	<.001	2	7
COAD	CHST11 →	-1.027	-0.290	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,649 associations by consensus.

PDZD11 vs PLEKHA5 — GBM

Explore this scatter interactively →