PDZD11

Across TCGA cell cohorts, PDZD11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,348 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDZD11-associated GO terms across cancer lineages are Transport of virus, Intracellular transport of virus, and Negative regulation of mRNA catabolic process. Each is linked with PDZD11 in more than 8 cancer types. Because this analysis shows association rather than direction, both PDZD11-to-partner and partner-to-PDZD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport of virus grouped by PDZD11-low versus PDZD11-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD11→partner) and Y-score (partner→PDZD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Transport of virus →	+0.142	+0.697	<.001	<.001	3	9
SOFT_TISSUE	Intracellular transport of virus →	+0.142	+0.697	<.001	<.001	3	9
LIVER	Negative regulation of mRNA catabolic process →	-0.073	-1.562	.004	.001	3	9
BONE	Regulation of sterol transport →	-0.095	-0.498	<.001	.001	3	9
BONE	Regulation of cholesterol transport →	-0.095	-0.498	<.001	.001	3	9
LARGE_INTESTINE	miRNA metabolic process →	-0.058	-0.413	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,348 associations by consensus.

Transport of virus by PDZD11 expression — SOFT_TISSUE

Explore this box plot interactively →