PDRG1

Across TCGA patient cohorts, PDRG1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,845 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDRG1-associated genes across cancer lineages are URI1, NEK2, and CENPF. Each is linked with PDRG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDRG1-to-partner and partner-to-PDRG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDRG1 versus URI1 in LSCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDRG1→partner) and Y-score (partner→PDRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	URI1 →	+0.829	+0.353	<.001	<.001	3	6
UCEC	NEK2 →	+1.118	+0.246	<.001	<.001	3	6
LSCC	CENPF →	+1.215	+0.414	<.001	<.001	3	6
BRCA	PLA2G5 →	-0.581	-0.333	<.001	<.001	3	5
LSCC	KIF11 →	+0.965	+0.375	<.001	<.001	3	5
LSCC	AURKA →	+0.806	+0.403	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,845 associations by consensus.

PDRG1 vs URI1 — LSCC

Explore this scatter interactively →