PDHA2

Across TCGA patient cohorts, PDHA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,835 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PDHA2-associated proteins across cancer lineages are ARL1, PECAM1_S729, and VSIR. Each is linked with PDHA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDHA2-to-partner and partner-to-PDHA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDHA2 versus ARL1 in BRCA, with a Pearson correlation of -0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDHA2→partner) and Y-score (partner→PDHA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARL1 →	-0.234	-0.021	.006	.003	3	2
OV	PECAM1_S729 →	+1.411	+0.050	<.001	.002	3	2
GBM	VSIR →	+0.520	+0.071	<.001	.005	3	2
GBM	WBP4 →	-0.259	-0.051	<.001	<.001	3	2
GBM	ZFHX3_S3432 →	+0.311	+0.045	.004	.004	3	2
BRCA	RNF40 →	+0.187	+0.030	.009	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,835 associations by consensus.

PDHA2 vs ARL1 — BRCA

Explore this scatter interactively →