PDGFB

Across TCGA patient cohorts, PDGFB protein abundance is significantly associated with the RNA expression of many other genes, with 7,769 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PDGFB-associated genes across cancer lineages are UQCRH, ZNF540, and CYSLTR1. Each is linked with PDGFB in more than 2 cancer types. Because this analysis shows association rather than direction, both PDGFB-to-partner and partner-to-PDGFB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDGFB versus UQCRH in BRCA, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDGFB→partner) and Y-score (partner→PDGFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UQCRH →	+0.826	+1.052	<.001	<.001	3	3
BRCA	ZNF540 →	-0.888	-0.720	<.001	<.001	3	3
HNSC	CYSLTR1 →	-1.148	-0.923	<.001	.009	3	3
UCEC	RN7SL138P →	-1.059	-0.399	<.001	.002	3	3
HNSC	LINC00996 →	-1.671	-0.812	.002	.002	3	3
BRCA	ABHD4 →	-0.629	-0.623	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,769 associations by consensus.

PDGFB vs UQCRH — BRCA

Explore this scatter interactively →