PDE6D

Across TCGA patient cohorts, PDE6D protein abundance is significantly associated with the RNA expression of many other genes, with 7,594 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDE6D-associated genes across cancer lineages are CNRIP1, SLC23A2, and AZIN2. Each is linked with PDE6D in more than 4 cancer types. Because this analysis shows association rather than direction, both PDE6D-to-partner and partner-to-PDE6D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE6D versus CNRIP1 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE6D→partner) and Y-score (partner→PDE6D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CNRIP1 →	+0.602	+0.225	.004	.003	3	5
OV	SLC23A2 →	+0.721	+0.296	.004	.005	3	4
HNSC	AZIN2 →	+0.716	+0.294	<.001	<.001	3	4
GBM	NLGN3 →	+0.945	+0.197	.007	.001	3	4
OV	STX2 →	+0.656	+0.295	.005	.001	3	3
LSCC	ATP5F1B →	-0.393	-0.121	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,594 associations by consensus.

PDE6D vs CNRIP1 — GBM

Explore this scatter interactively →