PDE2A-AS1

Across TCGA patient cohorts, PDE2A-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,316 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PDE2A-AS1-associated GO terms across cancer lineages are Protein localization to mitochondrion, mRNA 3'-end processing, and Vesicle localization. Each is linked with PDE2A-AS1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PDE2A-AS1-to-partner and partner-to-PDE2A-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to mitochondrion grouped by PDE2A-AS1-low versus PDE2A-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE2A-AS1→partner) and Y-score (partner→PDE2A-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to mitochondrion →	+0.062	+0.064	<.001	<.001	3	12
UCEC	mRNA 3'-end processing →	+0.064	+0.033	<.001	.002	2	13
STAD	Vesicle localization →	+0.057	+0.057	<.001	<.001	3	12
STAD	Positive regulation of DNA repair →	+0.060	+0.075	<.001	<.001	3	12
STAD	Regulation of DNA repair →	+0.059	+0.067	<.001	<.001	3	12
STAD	Mitochondrial transport →	+0.064	+0.051	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,316 associations by consensus.

Protein localization to mitochondrion by PDE2A-AS1 expression — STAD

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