PDCD2L

Across TCGA patient cohorts, PDCD2L mutation is significantly associated with the RNA expression of many other genes, with 353 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDCD2L-associated genes across cancer lineages are RNU6-527P, RNY3, and RNU6-693P. Each is linked with PDCD2L in more than 1 cancer types. Because this analysis shows association rather than direction, both PDCD2L-to-partner and partner-to-PDCD2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-527P grouped by PDCD2L-low versus PDCD2L-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD2L→partner) and Y-score (partner→PDCD2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-527P →	+0.436	+4.539	<.001	.008	3	2
COAD	RNY3 →	+2.090	+5.357	<.001	.006	3	2
COAD	RNU6-693P →	+1.117	+6.721	<.001	<.001	3	2
CESC	PCBP2P3 →	+0.047	+4.364	.009	.006	3	2
UCEC	WHAMM →	+0.563	+3.234	<.001	.009	3	1
UCEC	CABP1 →	-0.283	-3.459	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 353 associations by consensus.

RNU6-527P by PDCD2L expression — CESC

Explore this box plot interactively →