PCSK6-AS1

Across TCGA patient cohorts, PCSK6-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,175 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCSK6-AS1-associated proteins across cancer lineages are PCSK6, CEP131, and FGD3. Each is linked with PCSK6-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCSK6-AS1-to-partner and partner-to-PCSK6-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCSK6-AS1 versus PCSK6 in LUAD, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCSK6-AS1→partner) and Y-score (partner→PCSK6-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PCSK6 →	+0.812	+0.720	<.001	<.001	3	4
OV	CEP131 →	-0.437	-0.047	.003	.004	3	3
PDAC	FGD3 →	-0.299	-0.482	<.001	<.001	3	3
CCRCC	ABLIM3_S394 →	+1.083	+1.507	.005	.004	3	3
HNSC	NOC2L →	+0.248	+0.675	<.001	.001	3	3
OV	FBXO4_S48 →	-0.888	-0.052	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,175 associations by consensus.

PCSK6-AS1 vs PCSK6 — LUAD

Explore this scatter interactively →