PCNPP5

Across TCGA patient cohorts, PCNPP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,974 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCNPP5-associated GO terms across cancer lineages are Autophagosome organization, Regulation of autophagosome assembly, and Erythrocyte homeostasis. Each is linked with PCNPP5 in more than 27 cancer types. Because this analysis shows association rather than direction, both PCNPP5-to-partner and partner-to-PCNPP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome organization grouped by PCNPP5-low versus PCNPP5-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNPP5→partner) and Y-score (partner→PCNPP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Autophagosome organization →	+0.065	+0.460	.008	<.001	2	28
DLBC	Regulation of autophagosome assembly →	+0.081	+0.434	.001	.001	3	27
ESCA	Erythrocyte homeostasis →	+0.042	+0.218	<.001	<.001	3	26
ESCA	miRNA processing →	+0.084	+0.475	<.001	<.001	3	26
UVM	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.041	+0.132	<.001	<.001	3	26
ESCA	Insulin receptor signaling pathway →	+0.064	+0.392	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,974 associations by consensus.

Autophagosome organization by PCNPP5 expression — DLBC

Explore this box plot interactively →