PCK2

Across TCGA patient cohorts, PCK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,468 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCK2-associated proteins across cancer lineages are MTHFD1, ATAD2, and RBM47. Each is linked with PCK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PCK2-to-partner and partner-to-PCK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCK2 versus MTHFD1 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCK2→partner) and Y-score (partner→PCK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MTHFD1 →	+0.338	+0.518	<.001	.007	3	7
LSCC	ATAD2 →	+0.614	+0.708	<.001	<.001	3	5
GBM	RBM47 →	+0.584	+0.733	<.001	<.001	3	4
COAD	GPHN →	+0.354	+0.415	<.001	.001	3	4
LUAD	UBR7 →	+0.238	+0.404	.002	<.001	3	4
LSCC	SUPT16H →	+0.327	+0.553	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,468 associations by consensus.

PCK2 vs MTHFD1 — OV

Explore this scatter interactively →