PCDHGB7

Across TCGA patient cohorts, PCDHGB7 protein abundance is significantly associated with the RNA expression of many other genes, with 1,790 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDHGB7-associated genes across cancer lineages are ATP13A3, SLC15A1, and RPS3AP49. Each is linked with PCDHGB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGB7-to-partner and partner-to-PCDHGB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGB7 versus ATP13A3 in UCEC, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB7→partner) and Y-score (partner→PCDHGB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP13A3 →	-0.525	-0.431	.003	.003	3	2
LUAD	SLC15A1 →	-2.230	-0.924	.002	.002	3	2
BRCA	RPS3AP49 →	+4.989	+0.929	.008	.001	3	2
GBM	BDKRB1 →	-0.192	-1.343	.002	<.001	3	1
GBM	CST3 →	+0.807	+0.931	.004	.006	3	1
HNSC	PGK1 →	-1.420	-0.837	.007	.004	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,790 associations by consensus.

PCDHGB7 vs ATP13A3 — UCEC

Explore this scatter interactively →