PCDHGB7

Across TCGA pan-cancer cohorts, PCDHGB7 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PCDHGB7 data layer compared with 6 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PCDHGB7 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PCDHGB7 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PAAD show a favorable association.

KIRC, UVM, and LUSC are the cancer types where PCDHGB7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.590	0.357	.003	62	view →
UVM	DFS	Quartile	II,III,IV	0.422	0.953	.002	56	view →
LUSC	OS	Quartile	II,III,IV	0.274	0.660	<.001	19	view →
READ	DFS	Median	All	0.441	0.619	.020	19	view →
PAAD	OS	Median	All	0.705	0.466	.002	14	view →
UCS	OS	Tertile	IV	0.767	0.387	.024	12	view →
HNSC	OS	Median	III,IV	0.548	0.793	.004	12	view →
BRCA	DFS	Median	III,IV	0.590	0.398	.003	10	view →
ACC	OS	Tertile	IV	1.000	0.291	.024	7	view →
LGG	DFS	Tertile	All	0.638	0.353	.020	7	view →
SKCM	DFS	Median	IV	0.585	0.160	.028	6	view →
COAD	OS	Tertile	IV	0.781	0.301	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PCDHGB7–KIRC (DFS)

Open the KIRC breakdown →