PCDHGB7

Across TCGA patient cohorts, PCDHGB7 mutation is significantly associated with the RNA expression of many other genes, with 5,289 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHGB7-associated genes across cancer lineages are COX6A1P3, LCEP1, and TOMM22. Each is linked with PCDHGB7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDHGB7-to-partner and partner-to-PCDHGB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX6A1P3 grouped by PCDHGB7-low versus PCDHGB7-high in KIRC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB7→partner) and Y-score (partner→PCDHGB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	COX6A1P3 →	+0.173	+5.442	<.001	.005	3	3
HNSC	LCEP1 →	+0.198	+3.039	<.001	.006	3	3
UCEC	TOMM22 →	+0.323	+1.399	<.001	<.001	3	3
UCEC	CDKN3 →	+0.660	+1.977	<.001	<.001	3	3
COAD	LEPROTL1 →	+0.407	+1.939	.002	.003	3	3
UCEC	TNFRSF10A →	+0.468	+1.657	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,289 associations by consensus.

COX6A1P3 by PCDHGB7 expression — KIRC

Explore this box plot interactively →