PCDHGB7

Across TCGA patient cohorts, PCDHGB7 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHGB7-associated genes across cancer lineages are RAD51, Mre11, and PDCD4. Each is linked with PCDHGB7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDHGB7-to-partner and partner-to-PCDHGB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by PCDHGB7-low versus PCDHGB7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB7→partner) and Y-score (partner→PCDHGB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RAD51 →	+0.212	+2.330	<.001	.003	3	3
COAD	Mre11 →	+0.105	+1.874	.016	.047	3	2
UCEC	PDCD4 →	-0.483	-1.520	<.001	.003	3	2
COAD	Rad50 →	-0.188	-2.296	.036	.033	3	2
COAD	ASNS →	+0.445	+2.321	.002	.032	3	2
COAD	ATM →	-0.540	-2.459	<.001	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

RAD51 by PCDHGB7 expression — COAD

Explore this box plot interactively →