PCDHGB7

Across TCGA cell cohorts, PCDHGB7 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCDHGB7-associated genes across cancer lineages are PRR27, NUDT10, and C4BPB. Each is linked with PCDHGB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGB7-to-partner and partner-to-PCDHGB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR27 grouped by PCDHGB7-low versus PCDHGB7-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB7→partner) and Y-score (partner→PCDHGB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRR27 →	+0.017	+4.614	<.001	.004	3	1
BLOOD_Leukemia	NUDT10 →	+1.079	+3.491	<.001	.009	3	1
BLOOD_Leukemia	C4BPB →	+0.773	+3.318	<.001	.007	3	1
BLOOD_Leukemia	SYT16 →	+0.092	+3.584	<.001	.004	3	1
BLOOD_Leukemia	WNT3A →	+0.032	+3.754	.004	<.001	3	1
BLOOD_Leukemia	VWC2L →	+0.006	+3.076	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

PRR27 by PCDHGB7 expression — PANCREAS

Explore this box plot interactively →