PCDHGB6

Across TCGA patient cohorts, PCDHGB6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,247 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCDHGB6-associated proteins across cancer lineages are COMP, APBB2, and NRP1. Each is linked with PCDHGB6 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCDHGB6-to-partner and partner-to-PCDHGB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGB6 versus COMP in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB6→partner) and Y-score (partner→PCDHGB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COMP →	+1.237	+0.449	<.001	.001	3	4
BRCA	APBB2 →	+0.412	+0.464	<.001	<.001	3	4
HNSC	NRP1 →	+0.280	+0.750	<.001	.001	3	3
BRCA	TIMP2 →	+0.705	+0.461	<.001	<.001	3	3
UCEC	PDLIM4 →	+0.608	+0.592	.003	.006	2	4
GBM	RPL13_S140 →	-0.427	-0.692	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,247 associations by consensus.

PCDHGB6 vs COMP — BRCA

Explore this scatter interactively →