PCDHGB6

Across TCGA pan-cancer cohorts, PCDHGB6 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated PCDHGB6 data layer compared with 8 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PCDHGB6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PCDHGB6 expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRC show a favorable association.

BLCA, HNSC, and LUSC are the cancer types where PCDHGB6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.311	0.485	.001	52	view →
HNSC	DFS	Quartile	IV	0.680	0.417	<.001	45	view →
LUSC	DFS	Tertile	All	0.293	0.444	.001	43	view →
KIRC	DFS	Quartile	All	0.924	0.817	.003	37	view →
CESC	DFS	Quartile	All	0.471	0.737	.006	28	view →
SKCM	OS	Tertile	II,III,IV	0.426	0.232	.007	22	view →
OV	DFS	Quartile	II,III,IV	0.492	0.595	.023	20	view →
LGG	OS	Tertile	All	0.427	0.617	.003	19	view →
UCS	DFS	Tertile	III,IV	0.477	0.095	.010	16	view →
SCLC	OS	Median	II,III,IV	0.492	0.978	.021	15	view →
PAAD	OS	Median	II,III,IV	0.674	0.440	.002	10	view →
LIHC	DFS	Tertile	II,III,IV	0.450	0.134	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

PCDHGB6–BLCA (OS)

Open the BLCA breakdown →