PCDHB6

Across TCGA patient cohorts, PCDHB6 protein abundance is significantly associated with the RNA expression of many other genes, with 2,274 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHB6-associated genes across cancer lineages are TCF20, KCTD17, and STK4. Each is linked with PCDHB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB6-to-partner and partner-to-PCDHB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHB6 versus TCF20 in GBM, with a Pearson correlation of -0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB6→partner) and Y-score (partner→PCDHB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TCF20 →	-0.340	-0.386	.006	.006	3	1
GBM	KCTD17 →	-0.771	-0.386	.004	.006	3	1
GBM	STK4 →	+0.315	+0.386	.005	.006	3	1
GBM	FAM189A1 →	-1.204	-0.386	.005	.006	3	1
GBM	CEACAM4 →	+1.174	+0.386	.004	.006	3	1
GBM	GALE →	-0.536	-0.385	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,274 associations by consensus.

PCDHB6 vs TCF20 — GBM

Explore this scatter interactively →