PCDH19

Across TCGA cell cohorts, PCDH19 RNA expression is significantly associated with the RNA expression of many other genes, with 1,954 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PCDH19-associated genes across cancer lineages are UBTD2, SPSB4, and SOX2. Each is linked with PCDH19 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDH19-to-partner and partner-to-PCDH19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDH19 versus UBTD2 in BREAST, with a Pearson correlation of 0.38.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH19→partner) and Y-score (partner→PCDH19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	UBTD2 →	+0.781	+0.467	<.001	.004	3	3
SOFT_TISSUE	SPSB4 →	+2.474	+0.777	<.001	<.001	3	3
OESOPHAGUS	SOX2 →	+4.103	+2.422	<.001	.002	3	3
LARGE_INTESTINE	ADRA2C →	+1.855	+1.160	<.001	.003	3	3
SOFT_TISSUE	TAF11 →	+0.556	+0.868	<.001	<.001	3	3
SOFT_TISSUE	RGMA →	+2.042	+0.943	<.001	.001	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,954 associations by consensus.

PCDH19 vs UBTD2 — BREAST

Explore this scatter interactively →