PCDH1

Across TCGA pan-cancer cohorts, PCDH1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated PCDH1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PCDH1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PCDH1 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

COAD, LSCC, and HNSC are the cancer types where PCDH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	1.000	0.911	.022	78	view →
LSCC	OS	Tertile	All	0.916	1.000	.017	13	view →
HNSC	OS	Median	III,IV	1.000	0.449	.023	8	view →
LUAD	DFS	Quartile	III,IV	0.458	0.985	.016	3	view →
PDAC	DFS	Median	III,IV	0.509	0.204	.021	3	view →
GBM	DFS	Median	All	0.818	0.682	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

PCDH1–COAD (DFS)

Open the COAD breakdown →