PCDH1

Across TCGA patient cohorts, PCDH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,314 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCDH1-associated proteins across cancer lineages are PCDH1_S984, NIBAN2, and PCDH1_S962. Each is linked with PCDH1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PCDH1-to-partner and partner-to-PCDH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDH1 versus PCDH1_S984 in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH1→partner) and Y-score (partner→PCDH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PCDH1_S984 →	+0.788	+1.085	<.001	<.001	3	7
HNSC	NIBAN2 →	+0.423	+1.025	<.001	<.001	3	5
LSCC	PCDH1_S962 →	+0.286	+0.809	<.001	<.001	3	5
HNSC	PCDH1_S973 →	+0.676	+0.992	<.001	<.001	3	5
UCEC	FKBP11 →	-0.698	-0.887	.002	<.001	3	5
UCEC	EPB41L1 →	+0.575	+0.767	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,314 associations by consensus.

PCDH1 vs PCDH1_S984 — LSCC

Explore this scatter interactively →