PCDH1

Across TCGA cell cohorts, PCDH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,332 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PCDH1-associated GO terms across cancer lineages are Response to indole-3-methanol, Small GTPase-mediated signal transduction, and Response to steroid hormone. Each is linked with PCDH1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PCDH1-to-partner and partner-to-PCDH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by PCDH1-low versus PCDH1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH1→partner) and Y-score (partner→PCDH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to indole-3-methanol →	+0.233	+3.612	<.001	<.001	3	12
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.090	+3.210	<.001	<.001	3	12
STOMACH	Response to steroid hormone →	+0.086	+2.504	<.001	.002	3	12
OESOPHAGUS	Sensory perception of salty taste →	+1.528	+2.703	<.001	<.001	3	12
STOMACH	Paranodal junction assembly →	+0.376	+2.470	.003	<.001	3	12
LARGE_INTESTINE	Endoplasmic reticulum to cytosol transport →	+0.076	+1.187	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,332 associations by consensus.

Response to indole-3-methanol by PCDH1 expression — URINARY_TRACT

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