PCCB

Across TCGA cell cohorts, PCCB RNA expression is significantly associated with the RNA expression of many other genes, with 10,240 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PCCB-associated genes across cancer lineages are TRAP1, MRPL3, and RUVBL1. Each is linked with PCCB in more than 14 cancer types. Because this analysis shows association rather than direction, both PCCB-to-partner and partner-to-PCCB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCCB versus TRAP1 in BONE, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCCB→partner) and Y-score (partner→PCCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	TRAP1 →	+1.257	+0.756	.001	.001	2	15
UPPER_AERODIGESTIVE_TRACT	MRPL3 →	+0.862	+0.841	<.001	<.001	3	14
PANCREAS	RUVBL1 →	+1.022	+0.584	<.001	<.001	3	14
BLOOD_Lymphoma	CLUH →	+1.189	+0.711	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	ATP5F1B →	+0.991	+1.189	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	ATP5F1A →	+1.376	+1.233	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,240 associations by consensus.

PCCB vs TRAP1 — BONE

Explore this scatter interactively →