PCCA-DT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PCCA-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 13,402 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PCCA-DT-associated proteins across cancer lineages are PCCB, RASA2, and SH3KBP1. Each is linked with PCCA-DT in more than 5 cancer types. Because this analysis shows association rather than direction, both PCCA-DT-to-partner and partner-to-PCCA-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCCA-DT versus PCCB in COAD, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCCA-DT→partner) and Y-score (partner→PCCA-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPCCB →+0.514+0.625<.001<.00136
UCECRASA2 →-0.265-0.801<.001<.00134
HNSCSH3KBP1 →-0.456-1.050<.001<.00134
UCECTBC1D2B →-0.283-0.507<.001<.00134
HNSCTRIM2 →+0.721+0.794<.001<.00134
LUADGGCT →+0.397+0.623<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,402 associations by consensus.

PCCA-DT vs PCCB — COAD

Per-sample scatter of PCCA-DT vs PCCB in COAD (Pearson r = 0.34).

Explore this scatter interactively →

Exploration