PCCA-AS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PCCA-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,346 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PCCA-AS1-associated proteins across cancer lineages are PCCA, PCCB, and MAN2A1. Each is linked with PCCA-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCCA-AS1-to-partner and partner-to-PCCA-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCCA-AS1 versus PCCA in BRCA, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCCA-AS1→partner) and Y-score (partner→PCCA-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAPCCA →+0.514+0.370<.001.00334
BRCAPCCB →+0.495+0.362<.001.00234
GBMMAN2A1 →-0.392-0.423.003<.00134
BRCAESD →+0.332+0.241.001.00834
BRCATSC22D1 →+0.301+0.291<.001.00334
OVUTP18 →-0.238-0.310.001.00433
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,346 associations by consensus.

PCCA-AS1 vs PCCA — BRCA

Per-sample scatter of PCCA-AS1 vs PCCA in BRCA (Pearson r = 0.33).

Explore this scatter interactively →

Exploration