PAXX

Across TCGA patient cohorts, PAXX RNA expression is significantly associated with the protein abundance of many other proteins, with 11,335 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAXX-associated proteins across cancer lineages are EHMT1, SUPT16H, and UBR7. Each is linked with PAXX in more than 6 cancer types. Because this analysis shows association rather than direction, both PAXX-to-partner and partner-to-PAXX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAXX versus EHMT1 in COAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAXX→partner) and Y-score (partner→PAXX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EHMT1 →	+0.439	+0.652	<.001	<.001	3	7
LSCC	SUPT16H →	+0.421	+0.520	<.001	<.001	3	6
OV	UBR7 →	+0.377	+0.703	<.001	<.001	3	5
GBM	PPP4R2 →	+0.257	+0.318	.001	.006	3	5
LSCC	GTF3C4 →	+0.310	+0.495	<.001	<.001	3	5
OV	SSNA1 →	+0.602	+0.712	.005	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,335 associations by consensus.

PAXX vs EHMT1 — COAD

Explore this scatter interactively →