PAXIP1-DT

Across TCGA patient cohorts, PAXIP1-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 19,530 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAXIP1-DT-associated proteins across cancer lineages are MEPCE, STRBP, and GTF2I. Each is linked with PAXIP1-DT in more than 7 cancer types. Because this analysis shows association rather than direction, both PAXIP1-DT-to-partner and partner-to-PAXIP1-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAXIP1-DT versus MEPCE in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PAXIP1-DT→partner) and Y-score (partner→PAXIP1-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MEPCE →	+0.343	+0.768	<.001	<.001	3	8
LSCC	STRBP →	+0.608	+0.759	<.001	<.001	3	7
GBM	GTF2I →	+0.429	+0.487	<.001	<.001	3	7
LSCC	PUS7 →	+0.555	+0.792	<.001	<.001	3	6
HNSC	NRBF2 →	-0.438	-0.635	<.001	<.001	3	6
OV	SSBP1 →	+0.452	+0.654	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,530 associations by consensus.

PAXIP1-DT vs MEPCE — LSCC

Explore this scatter interactively →