Across TCGA patient cohorts, PARVB mutation is significantly associated with the RNA expression of many other genes, with 1,441 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PARVB-associated genes across cancer lineages are TRGV11, OR51A10P, and IGKV2D-19. Each is linked with PARVB in more than 2 cancer types. Because this analysis shows association rather than direction, both PARVB-to-partner and partner-to-PARVB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARVB→partner) and Y-score (partner→PARVB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRGV11 →	+0.121	+4.996	<.001	.002	3	3
LIHC	OR51A10P →	+0.062	+6.676	<.001	<.001	3	2
BLCA	IGKV2D-19 →	+0.157	+4.314	<.001	.009	3	2
CESC	EEF1E1-BLOC1S5 →	+0.042	+4.969	<.001	.004	3	2
CESC	NF1P10 →	+0.362	+5.569	<.001	.002	3	2
UCEC	CDCA2 →	+0.920	+2.584	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,441 associations by consensus.

Exploration

PARVB survival (RNA) · tumor vs normal (RNA) · all PARVB data types