PARP10

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PARP10 protein abundance is significantly associated with the RNA expression of many other genes, with 12,176 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARP10-associated genes across cancer lineages are OAS2, IFIH1, and STAT1. Each is linked with PARP10 in more than 8 cancer types. Because this analysis shows association rather than direction, both PARP10-to-partner and partner-to-PARP10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARP10 versus OAS2 in HNSC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP10→partner) and Y-score (partner→PARP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCOAS2 →+1.350+0.365<.001<.00139
HNSCIFIH1 →+1.084+0.375<.001<.00139
HNSCSTAT1 →+0.933+0.315<.001<.00139
HNSCIFIT3 →+1.675+0.335<.001<.00139
HNSCPARP9 →+0.867+0.346<.001<.00139
BRCAGBP5 →+1.597+0.317<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,176 associations by consensus.

PARP10 vs OAS2 — HNSC

Per-sample scatter of PARP10 vs OAS2 in HNSC (Pearson r = 0.57).

Explore this scatter interactively →

Exploration